Atsuro Saijo, MD, PhD
Research Interests:
My research interest is understanding the interaction between stromal cells and cancer cells in the tumor microenvironment. During my graduate work, I elucidated the interaction between stromal cells and cancer stem cells.
Recently, immune checkpoint inhibitors have shown promising results in several types of cancer. However, most patients experienced disease progression due to the resistance to the agents. Through my experience as a clinical oncologist, I strongly aim to expand my field of research to the areas of cancer immunology and joined Okada Lab to develop novel engineered T cells for glioma immunotherapy.
Email: atsuro.saijo@ucsf.edu
2004 M.D. Tokushima University, Japan
2018 Ph.D. Department of Respiratory Medicine and Rheumatology, Tokushima University,
Graduate School of Biomedical Sciences, Japan
2021-present Postdoctoral Scholar, Department of Neurological Surgery, UCSF
2015 Excellent Poster Award, Annual Meeting of The Japanese Association of Metastatic Research
Paclitaxel for relapsed small-cell lung cancer patients with idiopathic interstitial pneumonias.
Saijo A, Hanibuchi M, Ogino H, Otsuka K, Goto H, Nokihara H, Nishioka Y.
Mol Clin Oncol 10(5):541-546, 2019.
Bone marrow-derived fibrocytes promote stem cell-like properties of lung cancer cells.
Saijo A, Goto H, Nakano M, Mitsuhashi A, Aono Y, Hanibuchi M, Ogawa H, Uehara H, Kondo K, Nishioka Y.
Cancer Lett 421:17-27, 2018.
An analysis of the clinical features of lung cancer in patients with connective tissue diseases.
Saijo A, Hanibuchi M, Goto H, Toyoda Y, Tezuka T, Nishioka Y
Respir Investig 55(2):153-160, 2017.
Fibrocyte-like cells mediate acquired resistance to anti-angiogenic therapy with bevacizumab.
Mitsuhashi A, Goto H, Saijo A, Trung VT, Aono Y, Ogino H, Kuramoto T, Tabata S, Uehara H, Izumi K, Yoshida M, Kobayashi H, Takahashi H, Gotoh M, Kakiuchi S, Hanibuchi M, Yano S, Yokomisa H, Sakiyama S, Nishioka Y.
Nat Commun 6:8792, 2015.