Jacob (Jake) Young, MD
Jacob (Jake) Young, MD is a neurosurgery resident at the University of California, San Francisco with an interest in neurosurgical oncology and immunotherapy. He is a graduate of Duke University and the University of Chicago Pritzker School of Medicine, where he was elected to the Phi Beta Kappa and Alpha Omega Alpha Honor Societies, respectively. In medical school, under the guidance of Maciej Lesniak MD, his translational research focused on designing and investigating novel viral and immunological agents for the treatment of high-grade gliomas. In the Okada Lab, he is investigating the tumor-mediated immunosuppression in the context of glioma-neuronal functional remodeling, and he is studying the ability of focused ultrasound to enhance immunotherapy delivery. Additionally, he is interested in clinical trial development and is contributing to the translation of Okada Lab discoveries to active clinical trials at UCSF for patients with glioblastoma. He partners his laboratory work with clinical research exploring how to optimize functional outcomes and minimize complications after surgery for intrinsic brain tumors with direct electrical stimulation and brain mapping, where he works closely with mentors Shawn Hervey-Jumper MD, Manish Aghi MD PhD, and Mitchel Berger MD.
Email: jacob.young@ucsf.edu
2012, B.S. in Neuroscience, Duke University, Durham, NC
2017, M.D., University of Chicago, Chicago, IL
2021, Donald O. Quest Award, American Association of Neurological Surgeons
2020 – 2022, Chan-Zuckerberg Physician-Scientist Fellow
2021, Harold Rosegay Award, San Francisco Neurosurgical Society
2020, UCSF Exceptional Physician Winner
2019, Howard Naffziger Award for Excellence in Patient Care, Department of Neurosurgery, University of California, San Francisco
2018, Krevans Award for Excellence in Patient Care, Zuckerberg San Francisco General Hospital
Resection of supplementary motor area gliomas: revisiting supplementary motor syndrome and the role of the frontal aslant tract.
Young JS, Gogos AJ, Aabedi AA, ... Hervey-Jumper SL, Villanueva-Meyer JE, Berger MS.
J Neurosurg. 2021 Oct 1:1-7. doi: 10.3171/2021.4.JNS21187. Epub ahead of print. PMID: 34598138.
The benefit of early surgery on overall survival in incidental low grade glioma patients: a multicenter study.
Ius T, Ng S, Young JS, ... Skrap M, Duffau H, Berger MS.
Neuro Oncol. 2021 Sep 8:noab210. doi: 10.1093/neuonc/noab210. Epub ahead of print. PMID: 34498069.
Effects of ventricular entry on patient outcome during glioblastoma resection.
Young JS, Gogos AJ, Pereira MP, Morshed RA, Li J, Barkovich MJ, Hervey-Jumper SL, Berger MS.
J Neurosurg. 2021 Jan 8:1-9. doi: 10.3171/2020.7.JNS201362. Epub ahead of print. PMID: 33418530.
The Glioma-Network Interface: A Review of the Relationship Between Glioma Molecular Subtype and Intratumoral Function.
Young JS, Morshed MR, Gogos GA, Amara AD, Villanueva-Meyer VJ, Berger BM, Hervey-Jumper HS.
Neurosurgery. 2020 Nov 16; 87(6):1078-1084. doi: 10.1093/neuros/nyaa362
Association of Maximal Extent of Resection of Contrast-Enhanced and Non-Contrast-Enhanced Tumor With Survival Within Molecular Subgroups of Patients With Newly Diagnosed Glioblastoma.
Molinaro AM, Hervey-Jumper S, Morshed RA, Young J, ... Theodosopoulos P, McDermott M, Berger MS.
JAMA Oncol. 2020 Apr 1;6(4):495-503. doi: 10.1001/jamaoncol.2019.6143. PMID: 32027343; PMCID: PMC7042822.
Individual Differences in Dopamine Are Associated with Reward Discounting in Clinical Groups But Not in Healthy Adults.
Castrellon JJ, Seaman KL, Crawford JL, Young JS, ... Cowan RL, Zald DH, Samanez-Larkin GR.
J Neurosci. 2019 Jan 9;39(2):321-332. doi: 10.1523/JNEUROSCI.1984-18.2018. Epub 2018 Nov 16. PMID: 30446530; PMCID: PMC6325254.