Junya Yamaguchi, MD, PhD
Junya Yamaguchi, M.D., Ph. D. is a neurosurgeon licensed in Japan, currently working as a visiting scholar in the laboratory of Dr. Hideho Okada at the UCSF Brain Tumor Center (BTC). Throughout his career, he has been involved in the treatment of adult and pediatric malignant brain tumors. He received his Ph.D. degree from Nagoya University for his work on genomic abnormalities and chemotherapy sensitivity in primary central nervous system lymphoma. In particular, non-operative treatment of malignant brain tumors is his main interest. He realized the limitations of current treatments for malignant brain tumors and has conducted research on immunotherapy for malignant brain tumors in Japan. As his current primary interest is how to modify and elevate CAR-T therapy to clinical use, he came to Okada Lab to help bring CAR-T therapy to patients with difficult-to-treat malignant brain tumors.
Outside the lab: Watching and playing basketball
2022, Ph.D. in Neurosurgery, Nagoya University Graduate School of Medicine, Nagoya, Japan
2012, M.D., Nagoya University Faculty of Medicine, Nagoya, Japan
2023, Grant-in-Aid for Early-Career Scientists, JSPS. Title: Molecular mechanisms of altered susceptibility to RMPV therapy in mutation-positive PCNSL.
2022, Toyoaki Scholarship Foundation Overseas Travel Subsidy.
Latest classification of ependymoma in the molecular era and advances in its treatment: a review.
Yamaguchi J, Ohka F, Motomura K, Saito R.
Jpn J Clin Oncol. 2023 Jul 31;53(8):653-663. doi: 10.1093/jjco/hyad056.
Rapid detection of the MYD88 L265P mutation for pre- and intra-operative diagnosis of primary central nervous system lymphoma.
Yamaguchi J, Ohka F, Kitano Y, Maeda S, Motomura K, Aoki K, Takeuchi K, Nagata Y, Hattori H, Tsujiuchi T, Motomura A, Nishikawa T, Kibe Y, Shinjo K, Kondo Y, Saito R.
Cancer Sci. 2023 Mar 1. doi: 10.1111/cas.15762.
CD79B Y196 mutation is a potent predictive marker for favorable response to R-MPV in primary central nervous system lymphoma.
Yamaguchi J, Ohka F, Lushun C, Motomura K, Aoki K, Takeuchi K, Nagata Y, Ito S, Mizutani N, Ohno M, Suzaki N, Takasu S, Seki Y, Kano T, Wakabayashi K, Oyama H, Kurahashi S, Tanahashi K, Hirano M, Shimizu H, Kitano Y, Maeda S, Yamazaki S, Wakabayashi T, Kondo Y, Natsume A, Saito R.
Cancer Med. 2022 Dec 7. doi: 10.1002/cam4.5512.