Ryusuke Hatae, MD, PhD
Research Interests:
As a postdoctoral fellow in Dr. Tasuku Honjo’s laboratory, I worked on developing the host immune metabolic biomarkers in cancer patients treated with PD-1 antibody. I also investigated the correlation between exhausted T cells and immune metabolism.
My current work is focused on discovering novel combinatorial immunotherapies for glioma from the aspect of immune metabolism.
Other Interests: Outside the lab, I enjoy watching sports, having a drink with friends, and playing with my children.
Email: ryusuke.hatae@ucsf.edu
2007 MD, Kumamoto University, Japan
2013 Board-certified Neurosurgeon, Japan Neurosurgical Society
2016 PhD, Department of Neurosurgery, Kyushu University, Japan
2016-2019 Postdoctoral Researcher, Laboratory of Dr. Tasuku Honjo, Kyoto University, Japan
2019-2020 Assistant professor, Department of Neurosurgery, Kyushu University, Japan
2020-now Postdoctoral Scholar, Laboratory of Dr. Hideho Okada, UCSF
2020 Inamori Foundation Inamori Research Grants
2020 Mochida Memorial Foundation Research Fellowship Award
2021 Overseas Research Fellowships, JSPS
Combination of host immune metabolic biomarkers for the PD-1 blockade cancer immunotherapy.
Hatae R, Chamoto K, Kim YH, Sonomura K, Taneishi K, Kawaguchi S, Yoshida H, Ozasa H, Sakamori Y, Akrami M, Fagarasan S, Masuda I, Okuno Y, Matsuda F, Hirai T, Honjo T
JCI insight. 5(2) e133501, 2020.
Current issues and perspectives in PD-1 blockade cancer immunotherapy.
Chamoto K, Hatae R, Honjo T
Int J Clin Oncol. 25(5):790-800, 2020.
Prevalence and clinicopathological features of H3.3 G34-mutant high-grade gliomas: a retrospective study of 411 consecutive glioma cases in a single institution.
Yoshimoto K, Hatae R, Sangatsuda Y, Suzuki SO, Hata N, Akagi Y, Kuga D, Murata H, Yamashita K, Togao O, Hiwatashi A, Iwaki T, Mizoguchi M, Iihara K
Brain Tumor Pathology. 34(3):103-112, 2017.
A comprehensive analysis identifies BRAF hotspot mutations associated with gliomas with peculiar epithelial morphology.
Hatae R, Hata N, Suzuki SO, Yoshimoto K, Kuga D, Murata H, Akagi Y, Sangatsuda Y, Iwaki T, Mizoguchi M, Iihara K.
Neuropathology. 37(3):191-199, 2017.
Precise detection of IDH1/2 and BRAF hotspot mutations in clinical glioma tissues by differential calculus analysis of high resolution melting data.
Hatae R, Hata N, Yoshimoto K, Kuga D, Akagi Y, Murata H, Suzuki SO, Mizoguchi M, Iihara K.
PLoS One. 11(8):e0160489, 2016.