Understanding Immune Responses Linked with Progression of Glioma

Collaborating with the Costello Lab and other labs in the UCSF Brain Tumor Center as well as Immatics GmbH, we are integrating cutting-edge genomics, bioinformatics as well as peptidomics to develop molecularly targeted immunotherapy approaches in progressive glioma. This line of investigations also take advantage of the wealth of banked tumor samples available through the Brain Tumor Bank led by Joanna Phillips, MD, PhD, at UCSF Neurosurgery. 
 

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Kohanbash G, Carrera DA, Shrivastav S, Ahn BJ, Jahan N, Mazor T, Chheda ZS, Downey KM, Watchmaker PB, Beppler C, Warta R, Amankulor NA, Herold-Mende C, Costello JF and Okada H. IDH mutations suppress STAT1 and CD8+ T-cell accumulation in gliomas. J. Clin Invest 127 (4) 1425-1437 (2017). PMC5373859

Who works on this project in the Okada Lab?